Unmasking of Brugada syndrome by lamotrigine in a patient with pre-existing epilepsy: A case report with review of the literature

Brugada syndrome is an inherited cardiac channelopathy arising from mutations in voltage-gated cardiac sodium channels.Idiopathic epilepsy portrays a coalescent underlying pathophysiological mechanism pertaining to the premature excitation of neuronal voltage-gated ion channels resulting in the disruption of presynaptic neurons and the unregulated

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Multimorbidity in osteoarthritis

This review is focused on the issue of terminology in patients with multiple coexisting diseases in modern clinical practice.We articulate that multimorbidity is one of the leading problems in the field of public healthcare and that the treatment of these patients demands an integral approach derived from the combined nature of the pathology.It was

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A dynamic image enhancement method for mine

Aiming at noise, low image grey and little gray difference of dynamic monitoring image of coal mine, a dynamic image enhancement method was proposed.Original image is processed Carseat 4-8 by an improved histogram equalization method firstly and then dealt with illumination estimatation.The illumination image is normalized, while reflected light im

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